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How to maximize the effect of IGF-LR3?

February 11, 2019

How to maximize the effect of IGF-LR3?

Simple introduction of IGF-LR3

IGF-LR3 is  a protein, and more specifically a polypeptide hormone that, since it contains some of the same molecular structure as insulin, closely mimics the anabolic effects of insulin. It contains a sequence of 83 amino acids, and the arg3 in the name refers to arginine being in the third position in this amino acid sequence. IGF-LR3 responds to signals from growth hormone (GH), and it is the most potent growth factors in the human body that helps you to maintain lean tissue and helps your muscles grow by causing the splitting and forming of new muscle cells (hyperplasia).

While the most well-known property of IGF-LR3 is this muscle maintenance and building effect that helps many folks look better than their built-in genetics intended, there are several other benefits of IGF-LR3, including:

Faster recovery
Increased drive
Increased muscle retention
Increased physical performance
Increased effectiveness of the anabolic cycle
Rapid fat loss
Decreased effects of aging
Improved testicular health
More rapid sleep onset and body recovery during sleep

From a muscle gain or fat loss standpoint, it’s really only the top small percentage of seriously competitive bodybuilders and highly competitive athletes who would get any additional gains from adding IGF-LR3.  So it’s probably not necessary for the weekend warriors, the overweight post-New Year’s gym enthusiasts, or the average athlete – unless they are looking for a fast shortcut.

In this case, IGF-LR3 is going to help you get past your physical limitations, but this synthetic protein can have some serious side effects when not used properly, including intestinal, heart, and spleen growth.  Very advanced bodybuilders are meticulous and know what they are doing and are able to minimize or eliminate any negative effects by using the strategies you’re going to discover in the rest of this article.

To get the most benefit out of IGF, or any other Growth Hormone precursor, you must be familiar with GHRH’s and GHRP’s.

This is because when you combine these compounds with a peptide like IGF, they cause and amplify a natural pulse of Growth Hormone (GH) from your body. In a nutshell, GHRP’s release a pulse of GH, and then the GHRH’s release and amplify this pulse. Combining both GHRP and GHRH together, along with a peptide like IGF, can give more than double the effect of either alone.

What are GHRP's?

GHRP is short for “Growth Hormone Releasing Peptide”, and is a chemical class of growth hormones in the category of drugs known as GH Secretagogues that stimulate the body’s natural release of the natural growth hormone (GH). There are many peptides in the GHRP family but the four most common are GHRP-6, GHRP-2, Ipamorelin, and Hexarelin.

GHRP-6 is widely considered to be the most effective of the growth hormone releasing peptides.  There’s some controversy about that as some people prefer or report superior results with GHRP-2, which is often referred to as the “second generation” version of GHRP’s, but the choice between GHRP-6 and GHRP-2 really depends on the outcome you are looking for.

For example, compared to GHRP-2, GHRP-6 tends to cause a huge increase in hunger. So if you are trying to gain lean mass and muscle, stay very anabolic or are struggling to eat enough food to meet high calorie intake needs based on activity levels, then it make senses to go with GHRP-6. On the flipside, if caloric restriction and rapid fat loss are your goals, then GHRP-2 is going to be a superior choice compared to GHRP-6. GHRP-2 does indeed cause far less appetite stimulation, so it can be a more beneficial choice for someone trying to keep lean and keep their eating in check.

Ipamorelin (IPA) is also a synthetic peptide product that tends to be used solely for growth hormone (GH) release.  It can be dosed higher than GHRP-6 or GHRP-2, it has no effect on appetite nor on prolactin or cortisol.

Finally, Hexarelin is the most potent of the GHRP’s, and is used to significantly bump GH release when combined with IGF.  While it’s less desirable for long term use as it has a high rate of desensitization, resulting long-term in a need for higher and higher amounts, it can be paired in lower doses with the other GHRP’s for more gains. If you’re doing a short cycle of peptides and GHRP’s, you can give Hexarelin a try.

Ultimately, to maximize the effects of IGF, you should accompany any IGF use with a GHRP, and from what I’ve personally researched, the GHRP Ipamorelin appears to be the safest and most efficacious. Like the other GHRP’s, its primary function is to stimulate your pituitary gland to produce more growth hormone, and also like the other GHRPs, it has a two-fold mechanism of action, meaning that it causes an increase in GH through amplifying the natural growth hormone releasing hormone signal pathway, and also by suppressing the actions of somatostatin, which can lower growth hormone as you sleep.


What are GHRH’s?

GHRH stands for “Growth Hormone Releasing Hormone”.It’s literally a hormone (an amino acid peptide produced in the hypothalamus) that causes the release of another hormone. GHRH also stimulates any GHRP to increase the release of GH,  in addition, seems to have a significant positive effect on cognitive health.

The main form of synthetic GHRH that one would inject along with GH and GHRP is something called Mod GRF 1-29 (sometimes still referred to by its old name as “CJC1295 without DAC”).  The other most common type of GHRH is called “CJC1295Dac”. In a nutshell, the main reason to use this a GHRH in conjunction with GHRP and GH is to cause an even greater increase in GH than you’d get if you used GH by itself, and also to minimize the negative side effects of using GH by itself. Remember what you learned earlier: GHRP’s release a pulse of GH, and then the GHRH’s release and amplify this pulse.

How to Stack the Ultimate Growth Hormone Peptide Stack: IGF-LR3, GHRH & GHRP

So now that you know all about GH, GHRP and GHRH, let’s delve into exactly how you would “stack” these compounds. The best results from any peptides, especially those designed for growth hormone and taken to improve anabolism, fat loss, physique or overall health, are to combine specific combinations of peptides all at the same time. Sure, you would get some improvement by using one peptide at a time, but stacking these things is really where it’s at when it comes to experiencing significant gains in a short period of time.

One of the most popular and reportedly efficacious peptide stacks for improving overall body appearance, losing fat, and gaining muscle in away that does not harm the pituitary gland or shut down your own natural production of Growth Hormone is a combination of IGF-1 LR3 (the GH) ,Mod GRF 1-29 (the GHRH), and Ipamorelin (the GHRP).

To complete your peptide stack, you’ll need a GHRP, and the top peptide I recommend for this is Mod GRF 1-29. The use of a GHRP like this allows you to increase your body’s own production of growth hormone without taking excessive exogenous injected growth hormone. Mod GRF 1-29 is specifically known to help increase fat loss and increase muscle growth, improve the appearance of connective tissue and skin, and help you recover from injuries and workouts more quickly.

It’s also important to know that don’t have to cycle your use of Mod GRF 1-29, which means you can match your usage to your cycles of IGF-1 LR3 and GHRH, or you can use Mod GRF 1-29 all on it’s own whenever you need to slightly increase growth hormone levels in your body, such as during a mass gain phase or when you are injured. However, to maintain sensitization, if you are going to use Mod GRF 1-29 on an ongoing basis then make sure you are using the lower end of the recommended dose range, or taking the full-strength dosage just once per day right before you go to bed.

Mod GRF 1-29 is typically injected subcutaneously, intravenously, or intramuscularly, and it seems to be efficacious when administered in any of these ways. If you get a little nervous with needles or dislike experiencing too many injections per day or feel like a freaking pincushion, you can simply add multiple peptide solutions from your peptide stack to the same syringe to reduce the number of injections you need to do each day.

To get the maximum effect, you can inject a dose of 100 mcg of Mod GRF three times per day about thirty minutes before a meal (when insulin and blood sugar tends to be lowest), and incorporate it in a cycle along with the other peptides in this article for four to twelve weeks. If you’re simply going to use Mod GRF 1-29 on an ongoing, everyday basis, throughout the year in the absence of the other peptides in this article, then just take 100 mcg once per day, preferably right before you go to bed.


Where can I buy IGF and its stack?

For those who are ready to reap the benefits of IGF-LR3 just contact us by info@custompeptidestech.com for more info to get started it. We offer the best IGF and other stack price on the market, and guarantee the purest form of all peptides available and we also accept CUSTOM SYNTHESIS.
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